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In verse 52 of chapter al-Forqan, Allah, the Almighty says: “So, do not obey the faithless, but wage against them a great Jihad with it”. Though, the commentators have disagreed on the exact meaning of "Great Jihad", but by analyzing the vocabulary and content of the above-mentioned verse, we can get to answers. Given the lexicologists’ views of the concepts of "Great Jihad", the commentators’ viewpoints and the Qur'anic-narrative evidence, the meaning of "Great Jihad" can be clearly defined as ‘to use the utmost power against the apparent and non-apparent enemy by any means possible in the divine direction with emphasis on the greatness of such efforts’. This concept can be deduced through analyzing the context and content of chapter al-Forqan on the one hand, examining the meaning of the phrases of verse 52 of Forqan on the other. Moreover, the pronoun [to it], and its reference imply that great Jihad includes all "cultural, political, moral and ... efforts against enemy and the only means to wage such a war is to disobey enemy and refuse every offer he puts forward.